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KMID : 0359819940230091047
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Journal of Korean Neurosurgical Society
1994 Volume.23 No. 9 p.1047 ~ p.1054
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The Correlation Between the Clincaland Pathological Findings of the Intracranial Ependymomas
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이해철
김동원/권건영/이장철/손은익/임만빈/김인홍
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Abstract
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The clinical and pathological features were analyzed for 11 cases with intracranial ependymoma treated surgically at the Keimyung University Dongsan Medical Center during the years 1987 to 1992. Tumor histology was reviewed individually and
grouped
into
three categories (Categories I to III) according to the pathologic grade used by Nazar, et al6). The correlation between the pathologic grade and prognosis after surgery was investigated.
There were 2 cases (18%) with category I histology, 5(45%) with category II histology, and 4(36%) with category III histology. The high recurrent rate, short recurrent interval, high rate of cerebrospinal fluid seeding and poor outcome were noted
in
patients with category III histology.
The authors also investigated the recurrent interval according to the degree of tumor resection. The mean recurrent interval after surgery was 12 months in cases of subtotal resection and 33 months in a case of total resection. Tumors resected
subtotally showed response to radiation and chemotherapy.
In conclusion, the pathologic grade and the degree of tumor resection were regarded as important prognostic factors after surgery. Aggressive surgery with chemotherapy or radiotherapy were required in the management of intracranial ependymoma.
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KEYWORD
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